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The Cochrane Library. Accessible through the Wiley InterScience Website, the new interface to the Cochrane Library provides easy access to a collection of high-quality, evidence-based health care databases assembled by the Cochrane Collaboration and related organizations including the United Kingdom’s National Health Service NHS.

Established in , the Cochrane Collaboration aims to produce and disseminate reliable and up-to-date information to support decision making in health care. A wide and growing range of health, social, and economic topics are covered and can be utilized to determine the effectiveness and appropriateness of interventions, to develop guidelines, and to use in policy making. All users can search the databases free of charge from the Wiley Website and access abstract material.

Subscribers can search the databases and access full-text material. The Cochrane Reviewers’ Handbook is available from the Cochrane Library Website and is useful reading for any librarian wishing to understand the systematic review process more fully. Database coverage ranges from to the present, and the resource is updated on a quarterly basis. At the time of this review, over , records were available and searchable from the combined Cochrane Library database collection. In particular, 2, complete reviews and 1, protocols were available from the Cochrane Database of Systematic Reviews.

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Zika provides a vision for how to keep pace with a fast-moving research field. In , an outbreak of the then little-known Zika virus in Brazil was accompanied by a sudden spike in neurological conditions. Most striking were reports of Zika-infected mothers giving birth to babies with microcephaly — unusually small heads and underdeveloped brains. A surge in research on the virus swiftly followed, with over articles recorded on the PubMed database between the beginning of and May To make sense of this research deluge, the World Health Organization recruited Nicola Low, an epidemiologist at the University of Bern in Switzerland, to lead a systematic review of the Zika evidence.

The critical feature of a systematic review, which must occur before they’ve even started, Low explains, is the authors must define a protocol that states how they will identify, select and synthesize the evidence around a clearly formulated research question. This reduces bias and allows the review to be reproduced. Low and her team concluded that Zika infection during pregnancy was the most likely cause of microcephaly. However, by the time their review was published in January , it was already out of date.

In the eight months it had taken to synthesise the evidence and pass peer review, another 1, new Zika-related papers had been added to the scientific literature. The team set to work again and just over a year later published a second Zika systematic review. Knowing that this would also be immediately obsolete, they announced that they were transitioning to a “living systematic review”.

Instead of starting afresh for the next update, they would use their review protocol to provide regular updates that incorporate the very latest evidence. The unusually fast-moving Zika research field illustrates a broader challenge facing medical and scientific research.

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Established in , the Cochrane Collaboration aims to produce and disseminate reliable and up-to-date information to support decision making in health care.

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Jump to navigation. CSG updates have their own prioritisation system. The Collaboration advises that reviews should be updated every two years. To achieve this, a review team would have to start working on an update one year after their review was published. Therefore, when a review is published, our Information Specialist makes a calendar note to look at the review in a year later when she runs quick updating searches in MEDLINE and Embase to see if any new trials have been published. She checks how many studies are awaiting classification in the review, noting this and the date of the last fully incorporated search.

Based on the collated information, a decision is made — one of the following:. Non-priority updates are further classified as postponed for another year or stable, and this decision is published on the Cochrane Library. Ensuring priority reviews are up-to-date CSG updates have their own prioritisation system. Step 1: Running quick updating searches The Collaboration advises that reviews should be updated every two years.

Based on the collated information, a decision is made — one of the following: Priority update: suggest the review team start an update; Non-priority update: suggest the review team wait another year before assessing again whether to update.

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